Join date: Jun 29, 2021


Hepatitis C is an infection of the liver caused by the hepatitis C virus (HCV). Epclusa Cost in Usa It is one of the leading causes of chronic liver disease in the United States with the CDC estimating that between 2.7 and 3.9 million people in the United States are infected with chronic HCV.1 Over the past several years, a number of direct acting antivirals have been approved to treat the infection.In June 2016, the FDA approved Epclusa, a fixed-dose combination product containing sofosbuvir, an HCV NS5B polymerase inhibitor, and velpatasvir, an HCV NS5A inhibitor, for treatment of chronic hepatitis C genotypes 1, 2, 3, 4, 5, or 6. With its approval, Epclusa became the first antiviral indicated for all 6 major forms of HCV.This article highlights several key therapeutics areas with Epclusa that every pharmacist should know.According to the National Institutes of Health website DailyMed: "Epclusa is indicated for the treatment of adult patients with HCV genotype 1, 2, 3, 4, 5, or 6. It can be used in those with compensated cirrhosis, decompensated cirrhosis, or without cirrhosis.DailyMed notes that "Each Epclusa tablet contains 400 mg of sofosbuvir and 100 mg of velpatasvir. Cost of Epclusa in Usa The tablets are pink, diamond-shaped, and film-coated. Each bottle contains 28 tablet and is closed with a child-resistant closure. Epclusa should be stored below 30°C (86ºF) and dispensed in the original container.Epclusa is administered as one tablet taken orally once daily with or without food. The recommended treatment duration is 12 weeks in all individuals. In patients with decompensated cirrhosis (Child-Pugh B or C) Epclusa should be administered with weigh-based ribavirin.